Services

Weight Loss

Semaglutide

Semaglutide (GLP-1)

The breakthrough GLP-1 therapy delivering dramatic, physician-supervised weight loss results.

Why Patients Choose Semaglutide

Weekly Injections

Once-weekly subcutaneous injections make semaglutide simple to integrate into your routine with minimal disruption.

Significant Weight Loss

Clinical trials show average weight loss of 15–20% of body weight, making semaglutide one of the most effective options available.

Metabolic Benefits

Beyond weight loss, semaglutide improves blood sugar control, reduces cardiovascular risk, and lowers inflammation.

Lean Mass Protection

Every plan includes protein targets and resistance-training guidance so the weight you lose is fat, not the muscle that keeps your metabolism working.

Lab-Guided Dosing

A1C, lipids, liver enzymes, kidney function, and thyroid status guide how we titrate rather than following a one-size-fits-all schedule.

In-Person Care in Denton

Injection teaching, side-effect troubleshooting, and dose changes happen face to face with your provider at our Denton, TX clinic.

What to Expect

Consultation & Labs

Your provider reviews your health history, checks labs, and determines if semaglutide is the right fit.

Gradual Dose Titration

We start at a low dose and gradually increase over several weeks to minimize side effects and optimize results.

Ongoing Support

Monthly follow-ups with your provider to track progress, adjust dosing, and provide nutrition guidance.

Maintenance & Transition

Once you reach your goal we move to the lowest effective maintenance dose and build the nutrition and strength plan that protects your result.

Candidacy & Safety

You May Be a Good Candidate If

BMI of 30 or higher, or 27 or higher with a weight-related condition such as prediabetes, hypertension, or sleep apnea

Looking for long-term chronic weight management rather than a short course

Comfortable with a once-weekly self-administered injection

No personal or family history of medullary thyroid carcinoma or MEN2 syndrome

Safety & Monitoring

Not for use in pregnancy or while breastfeeding; discontinue at least two months before a planned pregnancy

Contraindicated with a history of medullary thyroid carcinoma or MEN2

Report severe or persistent abdominal pain, which may signal pancreatitis or gallbladder disease

Gallstones, dehydration, and constipation are the most common reasons for a dose hold

Diabetes medications such as insulin or sulfonylureas may need reduction to avoid low blood sugar

Denton Family Practice Clinic does not sell medication. Our providers evaluate, prescribe, and monitor semaglutide therapy or an appropriate alternative dispensed by a licensed pharmacy. Brand names are referenced for identification only.

Frequently Asked Questions

How does semaglutide work?

It mimics GLP-1 hormone to reduce appetite, slow gastric emptying, and improve insulin sensitivity for sustained weight loss.

How much weight can I expect to lose?

Most patients lose 15–20% of their body weight over 12–18 months with proper adherence and lifestyle changes.

What are the common side effects?

Nausea, constipation, and decreased appetite are most common, especially during dose increases. These typically improve over time.

What is the standard dose schedule?

Treatment generally starts at 0.25 mg weekly and increases every four weeks as tolerated. Many patients settle between 1.0 and 2.4 mg weekly — the goal is the lowest dose that keeps progress steady with manageable side effects.

How do I manage nausea?

Eat smaller portions, stop at the first sign of fullness, limit high-fat and fried foods, sip fluids through the day, and hold at your current dose instead of escalating. Persistent vomiting or severe abdominal pain warrants a same-day call.

Semaglutide vs. tirzepatide — which is better for me?

Tirzepatide targets both GLP-1 and GIP receptors and averages greater weight loss in trials. Semaglutide has the longest real-world track record and established cardiovascular outcome data. Coverage, tolerance, and your medical history usually decide it — your provider will walk through both.

Is compounded semaglutide the same as the brand product?

No. Compounded formulations are prepared by licensed pharmacies and are not FDA-approved products. We discuss the differences openly and prescribe what is clinically appropriate and available. We prescribe and monitor therapy; we do not sell medication.

Do I need labs before starting?

Yes — typically A1C, a comprehensive metabolic panel, lipids, and thyroid studies, plus a review of personal or family history of medullary thyroid carcinoma or MEN2, which are contraindications.

How long do I need to take it?

Treatment duration varies. Many patients use semaglutide for 12–18 months, with ongoing maintenance strategies discussed with your provider.

Is semaglutide covered by insurance?

Some insurance plans cover it for diabetes or weight management. We also offer competitive cash-pay pricing.

Can I combine it with other weight loss treatments?

Yes. Your provider may recommend combining semaglutide with lifestyle modifications, supplements, or other therapies.

What happens if I miss a weekly dose?

If it has been fewer than five days, take it as soon as you remember and resume your normal day. If more than five days have passed, skip it and take the next scheduled dose. Never double up.

Will I regain weight after stopping?

Studies show meaningful regain when the medication stops without a plan. That is why we transition to a maintenance dose or a structured off-ramp with nutrition, strength training, and continued follow-up.

Can it be used if I don't have diabetes?

Yes. Semaglutide is approved for chronic weight management in adults with a BMI of 30 or higher, or 27 or higher with a weight-related condition, regardless of diabetes status.

Does it affect birth control or other medications?

Semaglutide slows stomach emptying, which can alter absorption of some oral medications. Bring your full medication list — including oral contraceptives — so we can adjust timing where needed.

What should I eat while on semaglutide?

Prioritize protein at every meal, add fiber gradually, hydrate consistently, and avoid alcohol and greasy meals during titration weeks. Very low calorie intake is the leading cause of fatigue and muscle loss on GLP-1 therapy.

Do you treat patients from outside Denton?

Yes — patients come to us from Corinth, Argyle, Lake Dallas, Sanger, Justin, Krum, and Ponder for GLP-1 weight management with in-person monitoring.

Ready for a Primary Care Partner?

Book an appointment today and get comprehensive care close to home.

Serving Denton and surrounding areas.

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